Epidemiology in multiple sclerosis: a pilgrim’s progress
نویسندگان
چکیده
منابع مشابه
P 21: Epidemiology of Multiple Sclerosis in Khorasan Razavi Province
Introduction: Multiple Sclerosis is an autoimmune disease which demyelinates neurons. It is the leading cause of non-traumatic disability in young adults in many countries. According to the atlas of MS, the number of patients with MS has increased from 2.1 million in 2008, to 2.3 million in 2013. Although several studies have been done worldwide to clarify the epidemiological patterns of the di...
متن کاملProgress in Multiple Sclerosis Genetics
A genetic component in the susceptibility to multiple sclerosis (MS) has long been known, and the first and major genetic risk factor, the HLA region, was identified in the 1970's. However, only with the advent of genome-wide association studies in the past five years did the list of risk factors for MS grow from 1 to over 50. In this review, we summarize the search for MS risk genes and the la...
متن کاملGenetic epidemiology of multiple sclerosis.
Epidemiological studies of multiple sclerosis have been performed on almost an industrial scale over the past 90 years. Morbidity statistics have been used to generate aetiological hypotheses, to assess local needs for the provision of services and the allocation of resources, and to define the natural history of the disease. Methodological factors have limited the extent to which the many surv...
متن کاملThe epidemiology of multiple sclerosis.
Although the cause of multiple sclerosis (MS) is unknown, epidemiologic studies support both genetic and environmental components of susceptibility. Reports of clusters, small "epidemics," geographic variation in prevalence, and alteration of MS susceptibility by migration support an environmental factor (or factors). The higher risk for MS in Europeans and in relatives of patients and the exis...
متن کاملEpidemiology and multiple sclerosis a personal review
Epidemiology is the study of the natural history of disease. The proper measures of disease frecuency require a numerator (cases) and a denominator (population at risk). Incidence and death rates refer to new cases and to deaths per unit time and population; prevalence rates to cases present at one time per unit population. Incidence and prevalence rates arise from specific surveys for the dise...
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ژورنال
عنوان ژورنال: Brain
سال: 2013
ISSN: 1460-2156,0006-8950
DOI: 10.1093/brain/awt220